The Folding@home software is painless to install, and the life you help save may be your own!
My favorite improvement is to allow the PS3 to turn itself off AFTER the work unit is complete, enabling people who use it on the weekend only to complete work units, rather than powering down after a gaming session and letting the work unit results get stale.
Now, if Santa would be so kind ...
Would if I did. I pinged Swampy because I know he's involved. Don't have a PS3 myself.