A few notes:
There are now a heck of a lot of "extra crispy" 4400s out there. (As opposed to the 4400 original returnees who are "original recipe".)
Getting 4400 abilities can be costly. The price paid by Richard Tyler and The Farrell/Baldwin family is too high.
Jordan Collier's messiah complex just got a huge boost.
Despite Diana Skouris' best efforts, Maia now completely identifies with Collier's movement.
Marco Pacella, is now The 4400 version of Hiro Nakamura in Heroes. I don't think this was a totally accidental choice by the producers.
It's going to be a long wait to next summer, but Heroes does start in a week. :)
I taped it and didn't watch it yet, so what's above is about all I read of your post so far. I would have to agree, with maybe one exception: the diversion with Isabel becoming a child again and then having it reversed the following episode was just a waste of time. About the only good thing was Kyle's attempt to rescue her to cement their relationship.
I'll refrain from any other speculation or comments until after I've seen the episode (likely this afternoon or tomorrow.)