Notice that several of the mutations not at the purported “hot spot” did not lead to a difference in the protein sequence? Did you notice that the differences in amino acids due to the mutations NOT at your purported “hot spot” will still make a functional Vitamin C Synthase protein? Notice that the frameshift mutation present in all the Ape species, but not in the other animals, will lead to a STOP codon so that Humans and Chimps cannot make a Vitamin C Synthase gene and are therefore vulnerable to scurvy?Except that you are still wrong on the Human/chimp sequence, of course I did. I analyzed this years ago. The hot spot is still a hot spot. And I know that some mutations appear to be harmless. But those mutations could still code for something that we are, as of this moment, unaware.
The mutation which causes a frame shift in the human sequence occurs at a hot spot. It is obvious.
A hot spot based upon what? Your selected examples, three of which had the same deletion? That is hardly a comprehensive survey. Out of 17 codons only two were identical. 15/17 are “hot spots”?