My wife has this and is on Requip, which is only marginally effective. She has undergone a battery of tests to find the cause of her anemia as well. This study does state a causal relationship between the two.
I’m sorry to learn your wife is suffering too. I tried Requip four years ago and all it did for me was prolong the onset of the movement (what I call ‘torture time’). I’ve had bouts of anemia too and required a transfusion last year. Don’t know the cause either. A great source of information and support can be found at www.rls.org the boards there were very helpful to me. I’ve had this for 30 years and am now disabled from it...if you’re wife ever wants to talk or ask questions, pm me.
About 8 years ago I discovered that both of my brothers and my Dad also have it. I am Blood Type B+.
I found a Diet by your blood type book and got rid of the symptoms for about a month after giving up chicken and making sure I did not eat anything on my list of do not eats.
It is hard to live in America without chicken, and I’m sure there is a little in chicken gravy.
I put this on the Freepers network seeing if B+ Freepers could duplicate my findings...Not so.
I think it is diet related because there are evenings when I do not have it.
Latest thing is maybe acetylcholine. Mine shows up in the tendons in my legs and knees.
Someone said rub mustard on my knees. Well this should be interesting...
But you are right. There is no life after 5 p.m. unless you want to stand on those legs.