That will be the end of the series. This is the last season. My guess is that Pullo will go with Agrippa to assault Antony in Egypt, and as Vorenus is on Antony's side, they will end up facing each other on the battlefield.
I have been avoiding that prediction, but what else can they do?
This is my guess: Vorenus will be the Roman soldier who helps Anthony commit suicide. Since Pullo thinks he is the father of Ceasararion and would want to protect the child from Octavian, this will be a sticky situation. We know that Octavian had Ceasarion murdered as he was Julius Ceasar's only surviving child and potentially a rival. Octavia, by the way, raised Anthony's children by Cleopatra. Antonia was the daughter of Marc Anthony and Octavia and mother of future emperor Claudius. She committed suicide out of shame at the antics of her grandson Callligula. Why did the creators have to invent so many inaccurate details when the real story is so great?