The only negative is 10MM round is not on every gun store shelf.
That is true eric, so do what I do.
Order your ammo a case at a time from www.ammoman.com
I dont have a 10mm(always wanted one), but I did get 45acp ball from them, and a friend just bought a case of 308 match ammo from the company for his new DPMS Arms 308 M-4 style rifle.
Well, I stock up on the stufff every chance I get.
I love the 10mm, it carries a whollop, and is very manageable. I think it is the perfect self-defense round.