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To: neverdem

I'm wondering if raloxifene is similar to Fosamax, which is also used for osteoporosis.


3 posted on 04/18/2006 1:17:57 PM PDT by Dr. Scarpetta (A man's first duty is to his honor and conscience.)
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To: Dr. Scarpetta
I'm wondering if raloxifene is similar to Fosamax, which is also used for osteoporosis.

Not in any pharmacological sense. Raloxifene and tamoxifen work at estrogen receptors. Fosamax is in the class of drugs called bisphosphonates which, IIRC, were first used intravenously to treat cancers that had metastasized to bone. Their ability to halt osteoporosis was an accidental discovery, IIRC. But I'm not an oncologist, so don't quote me. But if a patient still had her teeth, osteoporosis and a high risk for breast cancer, guess which drug I would pick?

Lawsuit claims Fosamax caused tissue disease (osteonecrosis of the jaw)

4 posted on 04/18/2006 1:34:58 PM PDT by neverdem (May you be in heaven a half hour before the devil knows that you're dead.)
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