[neverdem]

Depressed? Appetite gone strange? Maybe the two are both down to leptin.© Punchstock

[GSlob]

That's why they say "fat and happy".

[Born Conservative]

Back in the 90's, the expectation was that Leptin injections would be used to treat obesity, much the same way as insulin is in diabetics. Of course, the research proved differently, and at the time, it didn't pan out.

[neverdem]

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[aimhigh]

Here's a different view of Leptin;

Italian researchers have found that blockade of the hormone leptin, which is primarily produced in fats cells, has beneficial effects on the induction and progression of experimental autoimmune encephalomyelitis (EAE) in mice -- the animal model of human multiple sclerosis (MS). In their study appearing online on January 12 in advance of print publication in the February 2006 issue of the Journal of Clinical Investigation, Giuseppe Matarese and colleagues from Università di Napoli "Federico II" suggest that leptin neutralization may be a potential way to both prevent and treat MS.

http://www.sciencedaily.com/releases/2006/01/060115155104.htm