My great-great-grandfather came down with a bad case of dysentery in the 1870s West Virginia. He had to travel to check on property he owned during his suffering. In the 40-50 mile trip, he had to make many a hurried detour into the bushes to accommodate his malady.
On one such detour, he glanced down and saw that he had squatted over a coiled rattlesnake. He ran so quickly that he ripped the crotch seam out of his pants, which ended up as nothing but two separate legs.
My grandfather used to laugh that his grandfather had promptly drowned the rattlesnake and then could not have a bowel movement for another month (and needed a laxative to accomplish that task then).
One of the many, many 'colorful' stories in my Appalachian family.
Another true story.
One of my sons came home earlier than usual from a weekend at the lake with friends. He kind of limped in and called me into the bedroom right away.
He immediately (and very wild-eyed) dropped his pants and his skivvies to reveal a pair of testicles the size of saddle bags.
He being (just slightly) the wildest of my three boys, my first thought was along the lines of a new and terrible STD.
I called a urologist and he said he'd meet us right away at the emergency room. The Doc told him to drop his drawers and my boy hesitated saying, "Doc, you've probably never seen anything like this!" To which I said, "go ahead son, he's seen everything."
Well, long story a little shorter, he was diagnosed as having gotten into some poison ivy while answering nature's call. Fluid collected in the testicles and since there is more loose skin there than anyplace else on the body, we had, "voila", saddle bags.