I was taking 800 daily, but I heard that flax seed oil contains E, so I cut back to 400. It's all a matter of what makes you actually feel better. For me, that's B complex, E, Ester C, CoQ-10, bee pollen, and flax seed oil. And lately I've been taking one of those little coated aspirins every other day. I feel great.
From the people who brought us the Food Pyramid, and fought like hell to deny the Atkins low carb diet.
In other words, Blue State Morons.
Yes, it's trial & error. I take many other food supplements as well. Used to lecture on nutrition, wrote articles for local newspaper, arranged for other lecturers, etc.