No, don't do that! You're just adding to the problem.
The reply addresses for both spam and e-mail viruses are virtually always bogus. You're just sending unsolicited e-mail, aka spam, to somebody who had nothing to do with the mail you received.
The idiots who built these bounce options into their spam filters have made the spam problem significantly worse. Bounces to forged addresses constitute some substantial portion of the spam out there. The same goes for viruses and the ill-conceived bounce functionality in some virus filters.
Good tip. I shall cease and desist forthwith.