I can't like a .45 because my hands are too small to hold it properly. I hear though, that someone makes a smaller capacity .45 with a smaller grip. If I run across one of those, then maybe!If you're talking autoloader, I can't recommend the Glock .45s highly enough. They have a great grip shape, even for small hands. The ergonomics are great, and I find it more comfortable to shoot than the Browning M-1911 style. I know that's heresy, but it works for me.
If you want a revolver, try Smith&Wesson, Ruger or Taurus in double action. I don't recommend single action revolvers except as curiosities.
I was looking at one Glock .45 with a laser site that really felt nice. Was thinking about that one too. I liked the feel of it.
That Glock autoloader might be what I mean! I have just had a couple guys tell me lately that someone is out with a .45 SemiAuto that has a smaller grip.
I wouldn't need a .45 in revolver. I have the best revolver already! My S&W .357.