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Well I was taking 4000 mgm until I gave my sister a perm before she went to Mexico last winter. I could NOT believe how long and thick her hair was. I then doubled my dose. It's not an overnight thing but it works. I also read a book on it written by the medical doctors that discovered it. If you don't take it with food tho, it'll make you feel like hurling.

Thanks for the info...I'll try and get up to speed with the MSM.

Cheers.

Andrew Lessman's Maximum Joint Effort is the most comprehensive, highest potency formula we have ever created for the healthy support of your joints and connective tissues. It combines high levels of the three most popular and effective supplement ingredients for the support and maintenance of healthy joints - chrondroitin sulfate, glucosamine sulfate and M.S.M (methylsulfonylmethane). These ingredients are selected to provide the building blocks and supportive nutrients that allow your body to naturally maintain healthy joint structure and function in the face of the rigors of daily life. The special ingredients in Maximum Joint Effort help to support the vital cartilage in your joints that is naturally worn down over time as a result of the normal wear and tear of daily use. Glucosamine and chondroitin sulfate are two of the best sources of mucopolysaccharides, which provide the essential building blocks and vital structural ingredients necessary to rebuild, support and maintain healthy cartilage and connective tissue. If these two essential structural ingredients provide the building blocks for your joint tissues, then the sulfur from M.S.M. is the mortar that holds your joints together. In combination, they help to maintain and fortify healthy cartilage and connective tissue throughout your body, especially your joints. Maximum Joint Effort also contains 120 mg. of curcumin, used traditionally for centuries for its soothing properties and to help support your hard-working joints. The natural ingredients in our ultra high potency Maximum Joint Effort formula provide one of the easiest, gentlest and most effective ways to provide natural support for maintaining healthy joints. Suggested Use: For the healthy support of your joints, consume the contents of one packet (7 capsules) daily with food or as recommended by a health care professional. For best results, consume Maximum Joint Effort with an additional 500 milligrams of Vitamin C daily.

a 2 mos supply look at all of the nutrients it replaces!