I only use aspirin, a natural compound.
Never trusted acetaminopen or ibuprofen, both synthetic.
I have never understood why the medical establishment pushes Tylenol as a safer alternative to aspirin. Aspirin has been used for more than 100 years and its precursor, willow bark, has been used for thousands of years. Aspirin is an analgesic, antipyretic, anti-inflammatory, antithrombotic, and antiviral. Tylenol is an analgesic that doesn’t even work for some people and has some antipyretic effects. There must be some $$ motive.