https://freerepublic.com/focus/f-news/4138406/posts
There’s dispute as to whether this includes presidential office.
It looks like either DeSantis resign from governor and campaign for president or remain as governor and not run for president.
If you are president you represent other states besides Florida.
You could try to make the argument, but there’s next to no chance it might fly.
Also, federal law supersedes state law, i.e. he is not barred Constitutionally from running and meets federal requirements for the office - so it would be an exercise in futility to try to apply to a federal office.