Mice from Hell 2.0, “Precision Mouse Models:” First came BLT mice… but why not use even more human organs? Next comes human lung transplantation, yielding BLT-L mice

NonVeniPacem ^ | 2/8/2022 | Mark Docherty

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Abstract “A major limitation of current humanized mouse models is that they primarily enable the analysis of human-specific pathogens that infect hematopoietic cells. However, most human pathogens target other cell types, including epithelial, endothelial and mesenchymal cells. Here, we show that implantation of human lung tissue, which contains up to 40 cell types, including nonhematopoietic cells, into immunodeficient mice (lung-only mice) resulted in the development of a highly vascularized lung implant. We demonstrate that emerging and clinically relevant human pathogens such as Middle East respiratory syndrome coronavirus, Zika virus, respiratory syncytial virus and cytomegalovirus replicate in vivo in these lung implants. When incorporated into bone marrow/liver/thymus humanized mice, lung implants are repopulated with autologous human hematopoietic cells. We show robust antigen-specific humoral and T-cell responses following cytomegalovirus infection that control virus replication. Lung-only mice and bone marrow/liver/thymus-lung humanized mice substantially increase the number of human pathogens that can be studied in vivo, facilitating the in vivo testing of therapeutics.”

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776695/

If you missed part one, it’s here: https://nonvenipacem.com/2022/02/07/the-deadly-new-world-of-vaccines-and-monoclonal-antibodies-introduction-to-humanized-mice/

Yesterday we learned about BLT mice. Today we get the next step, BLT-L mice. This “advance” takes the fully human mouse model that employed live human bone marrow, liver, thymus and stem cells, and adds Lung to the mix. Human lung transplanted into a mouse with a fully human immune system, in order to study… coronaviridae, among other things. This study is from August, 2019. Interesting, no?

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This is the second in a 5-part series exposing the grisly, evil, and ridiculous production of humanized mice & the subsequent development of monoclonal antibodies. I post part 1 a few days ago

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I am pinging you because you’re the only trad I know around here. Also I am not sure who is the gatekeeper of the pro-life ping list

[M Kehoe]

Ben and Willard will get these Dr. Mengeles.

5.56mm

[ebb tide]

Ping

[17th Miss Regt]

Bacon, lettuce and tomato mice??

[M_Continuum]

Is not this the same thing they are doing to pigs for transplants?

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Pretty much

This world is evil & the public largely has no idea what is going on, often times at their local university lab.

[M_Continuum]

It is about to get a lot worse. It’s past the point of no return. Think Crispr Therapeutic’s (can cut DNA or add to) and Beam Therapeutic’s (creates synthetic DNA). Quantum computers are coming online and Co.’s claim Ai has consciousness. Mice, Swine and humans are about to be lab experiments.

[dragonblustar]

This is just the tip of the iceberg.