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Directed Evolution II
Substack ^ | 21 September 2021 | Anandamide

Posted on 09/23/2021 7:48:19 PM PDT by Fractal Trader

There is old saying “Cats got your tongue”. It emerges when you are at a loss for words…. or potentially choking on a Nerd Sweater.

This is an excellent presentation on the evolutionary trajectory of SARs-CoVs-2 and just as fascinating as the genomics, is the content that is explicitly not spoken about. You see, NextStrain and GISAID all have alot of uncle Bills grant money and he loves vaccines so much, that he has over $100M in BioNtech stock and CureVac stock tucked away in the Bill and Melinda Gates Foundation. As a result, many people in the Epi space we affectionately refer to as the Nerd Sweater Mafia…. they know to never speak ill of vaccines. See if you can find the word vaccine anywhere in the first 24 minutes of this very well done analysis on the directed evolution of this virus.

The fascinating aspect of this presentation is that it highlights the mutational spectrum of C19 during 2021 and it is as clear as day that there is a massive enrichment for mutations in the spike protein compared to other parts of the genome.

There is also a lot of squid ink diverting the viewers attention as to the cause of this. Let’s look at the running hypothesis they float to explain such an enrichment of mutagenesis in spike.

1.Natural selection against Host immunity.

Note the language.. not vaccine immunity.. host immunity. Blame the victim some more and redirect attention from the obvious selective pressure going on with “Spike only vaccination” to those immunocompromised people (the ones you need to get vaccinated to save).

Note at 8:52 he mentions this is speculative as they didn’t see any of this happening in the Spring 2020 during the ‘first’ pandemic wave. Remember this point as the emergence date of C19 continues to back into October 2019 with WIV employees losing their sense of smell. The first wave (in Trevor’s eyes) is only the wave he could see with qPCR but he forgets that viruses with R0 this high are unlikely to be at their first rodeo when we wise up and point our sequencers at them.

They begin to see spike mutagenesis in the fall of 2020 but it really takes off in 2021. This is where they will play their magic tricks. They will claim this was witnessed before the vax roll out therefore the vax is innocent. Watch them like a hawk.

A fly in their ointment: You will also see them speak about convergent evolution being evident (min 20+) in the data which refutes their own chronological argument that attempts to blame this on pre-vax “partially immune” people. Convergent evolution is where the same mutations appear to evolve independently over and over again around the world as similar selective pressures are applied.

The polymerase doesn’t make random errors. It has propensity to make some of the same errors due to the sequence context of the virus. This means an ORF8 deletion can occur in Africa and Australia independently without anyone traveling between the two continents to spread it there.

There are also similar selective pressures being applied in geographically distant places. In some of these cases, we can see different RNA variants emerge across the globe which may differ at a RNA sequence level but code for the same amino acid change. Let’s take the UUC codon for Phenylalanine. You can mutate it to UUA or UUG and still code for the same alternative amino acid Leucine.

More than one way to skin a cat…. but dont skin cats!! We kill bats.

When you see evidence of convergent evolution, you need to take arguments that rely on “we saw this variant before the vax, therefore the vax didnt cause it” with a pound of salt.

To drive this speculative “partial immunity population” home, the author displays an outlier case of a patient who had COVID for 150 days and was surely a breeding ground for new variants that emerge under a clearly immunocompromised setting. They sequenced the virus throughout this fight to watch the evolution in a single patient over time. Fascinating stuff.

This is an important anecdote that actually better supports the narrative he’s not allowed to talk about as its one patient and to believe this is happening population wide would require something to weaken millions of peoples immune systems synchronously.


TOPICS: Conspiracy; Health/Medicine
KEYWORDS: antivaxxernonsense
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To: David Chase
Spell checker got me. I missed it.

Yea, spell checker. Uh huh.

Can't possibly be because you're stupit.

#AndThisIsWhyYoureAVaxRabbit


21 posted on 09/24/2021 9:50:21 AM PDT by bagster ("Even bad men love their mamas".)
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To: bagster

So, I sometimes post things on purpose or with a purpose.

Even Cat Tales. (It’s true BTW)

So I wonder if Anandamide has another name……like a Freeper name.
Writing style seems awfully familiar………

Oh never mind, it’s not like I’d pay a Ransom to find out. Note that.


22 posted on 09/24/2021 9:56:09 AM PDT by David Chase
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To: David Chase

Another clue, but not necessarily in the direction you are hunting:

Anandamide

(N-arachidonylethanolamine) is a brain lipid that binds to cannabinoid receptors with high affinity and mimics the psychoactive effects of plant-derived cannabiniod drugs.


23 posted on 09/24/2021 10:34:20 AM PDT by absalom01 (You should do your duty in all things. You cannot do more, and you should never wish to do less.)
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To: absalom01

Fascinating.

I was going to look it up, I thought it was a chemical.
Had to pop up and do something.

Thank you.

So you know whom I’m thinking it could be?


24 posted on 09/24/2021 10:58:25 AM PDT by David Chase
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To: David Chase
I was going to look it up, I thought it was a chemical. Had to pop up and do something.

Yea. You were gonna look it up. Uh huh.

#CleverBoy


25 posted on 09/24/2021 11:03:26 AM PDT by bagster ("Even bad men love their mamas".)
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To: David Chase

Yes, you weren’t subtle!


26 posted on 09/24/2021 12:28:58 PM PDT by absalom01 (You should do your duty in all things. You cannot do more, and you should never wish to do less.)
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To: Fractal Trader

Note that this thread got distracted from the important content in your original post.


27 posted on 09/24/2021 1:32:18 PM PDT by Tymesup
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To: bagster

Well I was going when I was at the web-site but I became amazed at the way it was laid out and the writing style, and phrases used.

So I forgot that and decided to share a real Feline story to rattle the cage of a Cat lover because although the Cat “won” it still lost.

😎


28 posted on 09/24/2021 1:33:49 PM PDT by David Chase
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To: grey_whiskers

“Evidence in real time at the genetic and/or amino acid sequence level, of the jabs applying selection pressure to the coof virus.”

That sounds so impressive. Did you study amino acid sequences and selection pressure in med school?


29 posted on 09/25/2021 12:05:58 AM PDT by Pelham (No more words, now we fight)
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To: grey_whiskers

Ha — speaking of partial immunity — seems to contradict the idea that this is a “novel” virus never seen before that’s going to kill us all cause we ain’t got no immunity. snort - what a pant load.

And it’s pretty clear from the various records, that the mutations are also due to wide spread vax in the middle of a pandemic-which is idiotic for public health - but then it ain’t really about saving lives - is it? SMH


30 posted on 09/25/2021 1:05:39 AM PDT by greeneyes ( Moderation In Pursuit of Justice is NO Virtue--LET FREEDOM RING)
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