Posted on 09/09/2021 6:58:17 AM PDT by numberonepal
Niacin and Melatonin work in synergy. The melatonin opens the gateway to cells and the inflammation within the cells. Niacin gets inside and kicks the crap out of it. We are all depleted of melatonin, so everyone's doses are different.
The Sweet Spot is when there is No Flush. Not even a tingle occurs. Hence, all the melatonin is being used up as well as the niacin to remove inflammation and restore the cells to homeostasis. The Flush is when excess niacin is not being used by the melatonin and goes to the skin capillaries.
The environmental stresses of modern life can lead to shortages of nutrients, especially melatonin and niacin, leading to the accumulation of free radicals and inflammation. The virus was targeted to affect the ACE2 receptors, which are regulated by melatonin and niacin. Once in your cells the virus consumes your energy, depletes melatonin, down-regulates the ACE2 receptors (especially in the intestines producing a leaky gut) giving the virus and spikes easy access to your brain and nervous system through the Vagus nerve.
The virus thrives in a melatonin/niacin deficient environment. The virus uses the energy from inflammation for its fitness (fuel). Supplementing melatonin and niacin reduces the inflammation that makes your body more vulnerable and reactivates your immune system to take care of the virus.
Over the course of life the lack of nutrients, especially melatonin and niacin, can't counter the progression of bad health behaviors throughout that life. New exposures like electronics, geothermal shifts, etc, a stressful life and poorer quality food these days all compound these deficiencies. Our continued dynamic deficiency in especially NIATONIN (niacin/melatonin) leads to the accumulation of more energy not expended out as per in. Because of this free radical electrons form and inflammation accumulates.
It's literally like the virus and covid pathogenesis, just slower.
These viruses or their gain of function research - whatever you want to imagine it is - have evolved since SARS-1 in 2000 to target these energy receptors; aka ACE2; what niacin and melatonin regulate.
It's a feasting ground for them (viruses).
Note:
Niacin and melatonin regulate ACE2 (Angiotensin-converting enzyme 2).
ACE2 is an enzyme attached to the membrane of cells located in the intestines, kidney, testis, gallbladder, and heart. ACE2 lowers blood pressure by catalyzing the hydrolysis of angiotensin II into angiotensin.
They're (viruses) thermodynamically attracted to people who have more inflammation for them to use for their fitness (fuel). These high expressed ACE2 (aka niacin receptors) along with the SR-B1 coreceptor right next to it - they (virus) sneak in this.
Note:
SR-B1 is a scavenger receptor class B type 1. It functions as a receptor for high-density lipoprotein. It is also know as CD36, a scavenger receptor class B member 3.
SR-BI/CD36 chimeric receptors define extracellular subdomains of SR-BI critical for cholesterol transport
https://pubmed.ncbi.nlm.nih.gov/25211142/
The SR-B1 is where HDL dumps off cholesterol from blood into tissue to prevent atherosclerosis. Because the cholesterol was leaking out of the tissue after it reached threshold, it can not contain it anymore due to too much pressure. As a result, HDL lowers because it's not getting developed in the liver anymore. The HDL has to attend to scooping more cholesterol back into tissue, and is used up real quick.
The virus then gets in cells and as it literally continues to consume your energy until it reaches a threshold it needs of energy to double (replicate). As it does this it depletes melatonin. It also makes it a lot easier if you have deficient melatonin. You can see now why unhealthy and older people who have not had enough melatonin and niacin as most at risk. They also have low HDL/high TG (triglycerides). The depleted melatonin makes the PDC receptor, already stunted from accumulated inflammation over a lifetime, from pyruvate to Acetyl-CoA even more stunted. Due to this melatonin gets gradually even more depleted into say long haul COVID. As soon as the virus meets threshold to replicate it moves out the mitochondria, and on to the next one (cell) like a bad ex-girlfriend. Repeat forward. This is why COVID long haulers flush like crazy with even 50 mg doses of niacin.
Note:
• Type I interferons (IFNs) derived from plasmacytoid dendritic cells (PDCs) are critical for antiviral responses
• Pyruvic acid or pyruvate is a key intermediate in the glycolytic and pyruvate dehydrogenase pathways, which are involved in biological energy production.
• Acetyl-CoA is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism.
As the virus leaves each cell, it and all the crazy inflammation it amplified [hypered], leaves melatonin depleted and stunts further the PDC from pyruvate to acetylCoA. This is needed for AAANAT receptor from tryptophan to serotonin to melatonin stunted too, and so melatonin isn't made more and more.
Note:
The key regulatory step in melatonin synthesis is catalyzed by arylalkylamine N-acetyltransferase (AANAT), which converts serotonin to N-acetylserotonin.
This leaves ACE2 downregulated, and happens especially in the intestines/colon.
This is how the virus/spikes - like IVM gains easy access to your brain/nervous system then - your gut becomes leaky with this ravaging of melatonin and inflammation. This gives easy access through the Vagus nerve to cross into BBB (blood brain barrier) and nervous systems where the most bang for the buck energy is for them.
Basically the virus/spikes have to deplete your already deficient melatonin and niacin to succeed and be thermodynamically attracted in the first place.
So keeping NIATONIN sufficient/repleting it takes back control of YOUR energy metabolism that the spikes try to take over for their food (energy).
It (NIATONIN) doesn't just push out inflammation. It allows T-cell differentiation (melatonin through ACE2 aka GPR109A expression). Then niacin comes in which is literally an innate/mandatory function of the recruitment and facilitation of T-cells, killer cells, and B cells. It induces phagocytosis, denatures, kills, and clears the virus as well as all pathogens and all toxins. It's a feasting grounds for them.
Note:
GPR109A (encoded by Niacr1) is a receptor for butyrate in the colon. GPR109A is also a receptor for niacin, which is also produced by gut microbiota and suppresses intestinal inflammation.
https://pubmed.ncbi.nlm.nih.gov/24412617/
NIACIN: https://purebulk.com/products/niacin-vitamin-b3-immediate-release?sca_ref=1004090.8JspdBHd04…
MELATONIN: https://purebulk.com/products/melatonin?sca_ref=1004090.8JspdBHd04…
Precision (0.000 g) Scale: https://purebulk.com/products/gemini-20-digital-scale?sca_ref=1004090.8JspdBHd04…
This graphic contains the protocol. Please read it all, especially the top portion where is says to eliminate certain things while using the protocol.
Agreed, the skin effect that I have is not acne, which has a bacterial component. Instead it’s more a proliferation of blackheads. That’s why I conjectured that this was where my cholesterol was going.
Ya, it was more like a bumpy rash than acne. It was only on my chest. I think it was a healing crisis. My MgCl2 and DMSO solution knocked it out in a few days.
Below doses for 125-190 lb (56-86 kg); Divide weight by 160 lb (73 kg), then multiply by below listed doses
30 MIN BEFORE LUNCH & DINNER:
BUTYRATE*
^1-2 teaspoons:
-https://www.amazon.com/Pure-Encapsulations-SunButyrate-TG-Promote-Function/dp/B07W645FMS
-https://ww.amazon.com/gp/aw/d/B08L44JBCD/ref=psdcmw_3773931_t1_B07W645FMS
OR
^1-2 caps:
-https://www.amazon.com/Healus-Complete-Supplement-Tributyrin-absorption/dp/B075NTPXY2
OR
^1 sachet:
-https://www.amazon.com/Butycaps-Tributyrin-Butyric-sachet-Sachets/dp/B077BLKJCX (better than their caps?)
OR
^1-2 caps:
-https://www.amazon.com/Healthy-Gut-Tributyrin-X-Generation-Digestion/dp/B09H68YHT2
OR
^1-2 caps:
-https://www.amazon.com/Designs-Health-Tri-Butyrin-Supreme-Three/dp/B08D9NMNNQ
OR
^1-3 caps:
-https://www.amazon.com/Gut-Health-Supplement-100-Caps/dp/B002QO08AU
+
β-HYDROXYBUTYRATE (BHB)
-https://purebulk.com/products/bhb-magnesium?variant=31148774457393 *
^8 g (1.5 tbsp); lower/raise to comfort
*absorbable Magnesium
…10-20 MIN AFTER LUNCH & DINNER:
NIACIN*
*If able, start 500 mg/dose (250 mg if sensitive): as butyrate (which gets cells more prepped for niacin) restores over 1st few days, comfortably glide up to ~1,000 mg/dose; then take advantage of even higher doses
-https://purebulk.com/products/niacin-vitamin-b3-immediate-release?variant=14294913515569&&sca_ref=1004090.8JspdBHd04 (faster ship: https://shareasale.com/r.cfm?b=772960&u=2941673&m=53326&urllink=&afftrack=)
^PUREBULK is the PUREST; choose DHL for international shipping, & use code, DMITRYKATS for 10% off
-If niacin needed ASAP: Whole Foods (FLUSH WARNING on bottle; SOLGAR, 365), Vitamin Shoppe, GNC;
https://www.amazon.com/Solgar-Niacin-Vitamin-Vegetable-Capsules/dp/B0001VUOMM; Health4All, Plain, NutriCost, NOW
_
COFACTORS
(Methyl-)B Complex (niacinamide/nicotinamide as only B3) - to comfort
-https://www.amazon.com/Designs-Health-B-Supreme-Vitamin-Capsules/dp/B002MAT56G
Taurine - w/ butyrate (+ BHB) to comfort
-https://purebulk.com/products/taurine
Vit C (natural source) &/or:
-https://www.amazon.com/INNATE-Response-Formulas-Vitamin-Effective/dp/B000JM7K52
Creatine (monohydrate) - to comfort
Selenium
-https://www.amazon.com/BodyBio-Selenium-Liquid-Mineral-2oz/dp/B00N24J2LO
Beef Liver
-https://www.amazon.com/Ancestral-Supplements-Grass-Liver-Desiccated/dp/B01MSBZYQW
Melatonin (up to 20 mg), Vit D3 (up to 3,000 IU), R-ALA, ALCAR—w/ butyrate-BHB—can help
—
Lower butyrate (+BHB) as you feel 💯. Niacin at least 800 mg/1-2x/day w/ some butyrate (+BHB) before + cofactors, to comfort then
bkmk
Let’s move over here, shall we for the sake of ransomnote.
Taking more niacin than you need is a bit of a misnomer. You are taking amounts that you CAN process as long as there is melatonin present IN THE CELLS to usher in the niacin. So if you BALANCE the melatonin and niacin they are both used up in the cells attacking inflammation. Viruses are attracted to inflammation.
I only trust the data. Thankfully I’ve been trained to do just that. Real studies, with real data. A lot of studies are deceptive because this crap runs so deep that people will pay researchers to come up with the answers they desire. The thing about niacin is that really good studies were done in the 40’s-60’s. Post war money funded just about anything you wanted to study.
I saw she fussed about it. I’m not a scientist or a doctor so I have been programmed my whole life to think it’s bad. I have what I need to get started so I’ll try it again.
Good luck and I’m here if you need coaching.
bbb niatomin info
How to use the Niatonin Bot on the Niatonin Telegram chat to get quick answers:
@NiatoninBot is the main Bot of the Niatonin chat and is used to communicate key concepts about the Niatonin Protocol by Dr. Dmitry Kats.
Use any of the following commands for assistance from @NiatoninBot.
/howto how to use the bot
/chatrules welcome to Niatonin chat room
/mindmap easy way to interact with the protocol
/socialmedia how to find Dr. Kats online
/contraindications what not to take while using Niatonin
/disclaimer we are all an experiment of one
/wheretobuy supplement recommendations
/donate how you can donate
/bookaconsult book a consultation with Dr. Kats
/protocol the most up to date protocol
/info more extensive information links within the chat
Thanks and I appreciate it! As long as it doesn’t do something toxic I will do fine on it. It doesn’t really cause that much flushing without the melatonin so with it things should be fine as long as it doesn’t cause other problems.
Since I hurt my foot I have a lot of issues. I’m seriously depressed, can’t sleep without a lot of meds, gaining weight due to not being able to walk like I did, etc. I’m hoping it will help with all of that.
I’m desperate to find something. Still, I’m keeping my Ivermectin for a Covid infection. :-) I’m just not doing any prevention with it.
quick start protocol
Oh, and I do read articles praising it. I want both sides.
https://www.onlineholistichealth.com/the-niacin-flush/
IF it’s inflamed, it will help.
Circulation in that ankle/foot is bad so I have burning pains in it in the winter if it gets cold. I took about 150mg this morning and had a bearable flush. Once that was over the foot wasn’t burning and tingling. It would be worth trying just to make that one thing better.
Exactly my response—a serious melatonin dosing!
That kind of dosing is old news. Presently the protocol calls for producing your own melatonin and only supplementing when necessary (severe flush). Creating your own melatonin is done through butyrate consumption.
I’ve been doing 2500N pretty regularly lately, twice a day, starting the day off with two capsules of butyrate along with many of the other factors. I take taurine occasionally, but haven’t quite made it part of my regimen. I’m using hot yoga (via Hotworx) as my sauna experience.
One thing I’ve noticed that I may not have mentioned before is improved typing. I’ve always been a pretty fast typist. (One of the best things I ever did was take a typing class in 10th grade, over 50 years ago.) But I’ve always had a high error rate, reducing my net typing speed. I notice now that I make fewer errors in typing.
Another addition to my self-improvement lifestyle is an expensive electronic frequency device. This was recommended by a Brit friend to help heal Mrs. AZLiberty’s recently cracked kneecap, but it has a hundreds of modes to help with sleep, energy, fitness, chakra maintenance, focus, pain, learning, skin care, bioenergetic harmony, etc. It has a 14-day money-back guarantee, so I’m trying out everything I can (without overdoing it — frequency fatigue is a thing).
The first cycle I tried was called “Pure” — it’s basically to get your overall body right before working on specific things. After 20 minutes with the electrodes attached to my arms, I realized I was feeling exceptionally happy, and it continued for quite a while after the 1-hour session. The first time I tried the “Sleep” program, I was amazed with the depth of my sleep — it was like a near-death experience. Last night I tried it again and had seven hours of perfect sleep, without moving from my original position.
More fun.
T = 30+ minutes before food
T+0 Melatonin: 0.5-20 mg, until butyrate generates enough melatonin
T+10 Butyrate: 2-4 capsules to start, use less as need dissipates
T+20 Beta-Hydroxybutyrate: 6-18 g, depending on need
T+30 Food
T+60 Niacin: start at 500 mg per dose, increase over days to 3 g (if tolerable), then ease back to at least 1 g for maintenance
Co-Factors
Vitamin B Complex: every day or every other day
Vitamin C (natural food source): daily
Taurine: 800-1600 mg, with the butyrate
Selenium: 100-200 mcg, with the butyrate
Creatine monohydrate: 5 g (?), right before niacin
Grass-fed beef liver (for real Vitamin A, B12, copper, iron): 2 caps right after meals.
Auxiliary
Vitamin D3: up to 3000 IU, with the butyrate
R-Alpha Lipoic Acid (R-ALA): 200 mg, with the butyrate
L-Acetyl Carnitine: 600 mg, occasionally to comfort
Product Links
I noticed the name of the Niatonin Telegram thread changed to “GPR109” for a while, but is now back at “Niatonin”.
Is this a Rife device?
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