I’m a biochemist by education, and worked in Public Health related fields for 35 years before retiring 5 years ago.
I’m going to get the Johnson & Johnson vaccine. Why?
mRNA vaccines are new technology, and the longer term effects haven’t been adequately studied, in my opinion.
Studies are showing that the mRNA may be “fragile” and the injection you receive may not even have enough to generate the desired immune response.
J&J is a traditional vaccine technology. Vaccines have shown to be effective in preventing many, many illnesses over the decades (smallpox, polio, measles, etc.).
I’m not terribly worried about a tragic outcome if I contract Covid, but I do want to do some traveling in the near future, and would prefer not to contract it while away from home, just in case, so I’ll take the vaccine and hope it confers immunity.
You seem to be a person with knowledge of vaccines and I would like to know what your thoughts are in the future.
Hope you have safe travels.
I agree I am enrolled in the JNJ Ensemble 2 trial which is their backup plan to the 1 stick already approved. Which if that happened they told us we would be unblinded and if we got placebo they would give us real thing. Novavax has a good one I have a nephew in their trial. The real interesting one is the “plant based” Meticago vaccine (Canadian outfit) that my sister is in a trial for.
And your other concerns are legit minus the fractured mRNA -- dude, you know recombinant mRNA at even 55% titer is going to accomplish the task, unless your endocrine system is completely shot or cirrhosis.
Both Pfizer and Moderna's mRNA shot are overkill -- fortunately for Pfizer the true overkill halo has fallen to Moderna.
I agree with your take. If I get vaccinated it will be an actual vaccine and that’s J&J. I’m 72, in good health and get very little exposure. I’m in no hurry.