That being said, my wife, due to age and medical conditions, can easily rack the slide on her Ruger SR22, but cannot rack the slide on a Ruger LCP (.380,) Glock 42 (.380,) or Glock 26 (9mm.) Nor can she easily pull the DA trigger on a .38 S&W J Frame.
Therefore, I'd much rather she carry the SR22 than carry nothing at all.
You may be interested in this easy to rack 380 semiauto.
https://www.smith-wesson.com/firearms/mp-380-shield-ez-0
“The .22LR is totally inadequate for self defense.”
Bobby Kennedy, Ronald Reagan, the world record grizzly bear in the 1950s, and tens of thousands of other beg to disagree.
Look into the S&W M&P Shield .380 EZ. Insanely easy to rack the slide.