I don't think Obama ever particularly liked the Clintons and resented having to live up to his pledge to support her in 2016. Perhaps Obama was hoping all that time that she would never actually get the nomination. He was probably secretly rooting for Bernie Sanders.
Anyway, his support for Hillary during the 2016 general election seemed lukewarm and he appeared to be going through the motions when he had to speak on her behalf. It was telling on Election Night when it became obvious that Trump would win that Obama called Hillary and basically ordered her to concede. Remember that Hillary had no plans to concede that night and she put Podesta out there to send her supporters home. It was Obama that basically talked sense into her and shortly after that, she made the call to Donald Trump.
Two days later, Obama warmly welcomed Trump to the White House. I think it was not so much warmth towards Trump but private relief that it was not Hillary he was handing the White House over to.
Throughout the Obama Administration, it was still pretty much still the Clintons' Democrat Party and I think Obama has had quite enough of the Clintons. Think about it. In the year since the election, almost nobody talks about Obama anymore. Yet Hillary is everywhere in the media. It's almost like Hillary is the ex-president and that the eight years of Obama never even happened. So yes, I think Obama is sick and tired of the Clintons as are most of the rest of the Democrats.
"You're likeable enough, Hillary...".
I do believe he grudgingly admired Bill though, for his political acumen and ability to connect with people.