If you can’t operate a safety, get a Glock.
...or a double-action revolver.
most 1911s would probably fit the bill too.
I once read a story (in a book called “Death in the Tall Grass”) about a hunter who got so wound up when he saw a lion that he operated the bolt on his rifle 4 times without ever pulling the trigger once. Afterward when the his guide asked what happened the guy actually thought he was shooting and missing. The lesson above is less about knowing how to operate your weapon and more about not panicking.