It appears the cargo door partially opened and came close to tearing out completely.
The cargo door is that rectangular structure somewhat to the right of the hole, just above the head of the guy in the suit talking on a cell phone.
The hole appears to be a ripped off fairing/panel, but not one that is designed to come off. Can't really tell if it was ripped off by aerodynamic forces, say after an edge failed due to stress or corrosion, or if something pushed it out from inside.
It appears the cargo door partially opened and ...???
Take a second look at the 2nd pix in post #24 and issue a revised analysis please.