Cruel in the context of this world. Cruel to the baby, for the parents and extended family.
Do you believe in the theory of intelligent design? If so, then perhaps you might turn your own question around and share how the theory reconciles inefficiencies such as the list of birth defects provided above.
I don't believe or disbelieve. I find both a designed cosmos and a designer-less cosmos hard to comprehend.
As to reconciling a designer with birth defects, perhaps the designer had cruel intent. Intelligence doesn' t equal kindness here on earth. Perhaps the same with the designer.