Every large-scale terrorist attack (WMD or conventional) should be responded to in this way.
Lot's of innocents would die, but lot's of innocents live's would be saved, too.
And after several of thier wretched cities were leveled this way, I think we would see a LARGE decline in terrorist activities.
London gets rocked, Mecca gets leveled. Chicago gets rocked, Damascus gets leveled......
That's right and we have a lot more weapons than they do and can sustain our campaign. Do as Truman promised "A rain of ruin that the likes the world has never seen" will befall them.