I used an ozone system when I worked in a dialysis clinic to disinfect the water lines. It worked but it was hard to maintain a high enough concentration.
We went back to chlorine which always works.
I now maintain pools.
Why not a salt chlorination system? They work very well.
Salt Chlorination for my plant would not work because we needed high purity water.
I never really looked into salt chlorination so don’t know much about it.
What we used specifically for bio-control was Sodium Hypo-chlorite. Nasty stuff.