She gets sick in the middle of a campaign-that would be bad. Don’t know much else about her. In 20 years he’ll be mid 60’s. Still young enough but the ship may have sailed-think Jeb.
Presidential wives have to be iron ladies.
DeSantis appears to carrying all the weight in the family
That said, it would be natural as breathing for DeSantis to be picked up for cabinet positions in a Vance or Rubio presidency.