Alcohol is poison. Just finished reading a bio of Beethoven, whose last years were absolute torture for him due to his cirrhosis of the liver. The MDs description of the state of his organs during autopsy is horrific. He never listened to his doctors’ pleadings to stay off wine, Madeira, etc. and died at 55. Although, astonishingly, he composed some of his greatest works in between bouts of agonizing pain and suffering.
You can definitely see the aging effects of alcohol in people in their 50s and 60s compared to those who don’t drink.