Nattokinase is an enzyme derived from fermented soybeans with fibrinolytic (clot-dissolving) and antithrombotic (blood-thinning) properties. Eliquis is a direct oral anticoagulant that inhibits Factor Xa to prevent blood clots. Combining them can additively increase the risk of bleeding, which may be severe or life-threatening.
Medical sources and reviews explicitly advise against this combination:
While direct large-scale clinical trials on this specific pair are limited, the theoretical and documented risks (e.g., excessive bruising, nosebleeds, internal bleeding) lead experts to recommend avoidance.
It is wise to take those lrecautions seriously. I wzs on prednisone once, and was tak8ng ginko biloba and aspirin at the same time just to get through the day energy-wise and as pain free as possible. Little did i know what was hzppening.
Long story short. I felt neauseus, snd went to a convenient store bathroom. Stood in fron t of sink, trying not to throw up. The room started spinning and immediately i knew “This aint good”.
Woke up wedged between the toilet and wall... blood and black puke all over me, all over the sink. The walls. I couldnt beleive how much there was. I was soaked in it.
Stumbled out of bathroom, and flsgged a cop over. He tok one look at me, at the bathroom and immedistely called ambulance and off i went to hospital.
Came very c.ose to dying that day. Had to get transfusions to stay alive.
Turns out the biloba, a blood thinner, and aspirin together is a no-no. Little did i realize. Caused stomach ulcer that bled.