Let me outta here! Let me outta here!
People with MTHFR mutations (there are five known mutations, and 90% of the population have at least one; I have three) cannot process synthetic folic acid, which means they cannot process B vitamins. The folic acid builds to toxic levels in the liver. Symptoms of toxicity include anxiety, insomnia, depression, bipolar disorder, migraine headaches, and other neurological disorders.