“The problem causing sepsis is that we run out of Vitamin B1 (Thiamine), it appears.”
Please note that I even qualified this comment with “it appears.” The write up also makes a similar judgment, saying:
“With a new study, the research group has now uncovered why and how this can be counteracted: an acute shortage of vitamin B1 in the mitochondria—the cell's energy factories—forces another molecule, pyruvate, to be converted into lactic acid.”
I see in the comments appending that Paul Marik, who once commanded an EVMS team in this area, but retired (was ejected? also from NIH?) from his position for his stance and work on damming the COVID-19 panic, once again appears to have been at the fore of this curative treatment for sepsis, previously having long ago anticipated the application of B1/C to sepsis (blood poisoning), way before the Dutch contingent whose investigations you found and posted now.
I have entrusted my own personal approach toward the C19 dilemma based on the reports from Marik et al. at the beginning of the 2020 virus situation: I immediately adopted the quercetin/vitamin C/Zn+ protocol, together with vitamin D3 as also urged by others, and have suffered no C19 infection except one that hit briefly in January 2023.
With the quercetin-ionophore/zinc environment, the virus replication was immediately blocked. Since the effects lasted less than two days, with complete relief from it before I could even get an appointment with my NP health advisor. His observation and approval following His tests showed positive C19 infection, but that it was no longer active.
There have been no more such incidents, none before or since, even though I have engaged in no preventive measres except normal cleanliness and prophylaxis. I have used the useless but situation-required distancing and masking practices only when required.
But over and above that history, since adding these substances I have experienced effects from no other respiratory infections (flu, colds) which previously I had become accustomed to! My healthiness has been better than ever before.
Before ever seeing your heads-up article, I had already added both B1 and benfotiamin to my daily complement of substances because of the recommendation of my primary physician that was meant to address symptoms of peripheral nreuropathy experienced in my fingers and feet. The B1 theme has not seemed much helpful so far, but maybe not enough of these substances. As aside note, the label of the benfotiamine capsules says "Blood Sugar Support" and under that. "300 mg -- Maximum Strength" to be takenonce daily.
So what I am saying is that the prehistory of discovery that was fully applied by the Marijk team is of great assurance to me for personal application. I trust their work on sepsis far more than the scenario presented in the article you posted, or your initial comment. If there is a difference, it resides in the perceive multiplication of usefulness by adding glucose to the protocol. But this raises a question as to the application to diabetics, who cannot properly process glucose.
Thank you again for bringing this to the attention of the FR forum, me in particular.