There are lots of other problems. The dire wolf may have gone extinct because some of the traits that the boffins tried to re-edit back in to the gray wolf DNA were detrimental to the dire wolves. Did the editing back in cause a frame shift in the DNA.?..that could lead to all sorts of protein synthesis problems. Did the size of the DNA change...possibly leading structural DNA problems or epigenetic control issues?
Time will tell if the edited wolf babies survive and can make with other edited wolves.
“can MATE”....not “can MAKE”