There has been research on lie detection using functional MRI. (fMRI). As of now this technique isn’t fully developed as well as being too expensive, intimidating, and invasive for widespread use. Personally, I’d like to see this research hit a dead end, because I’d like there to be some shred of personal privacy, but that’s a discussion for another time.
I think every interrogation room should have a fridge filled with hypodermic needles and vials of sodium pentothal.