This approach sounds solid.
My PSA began increasing about 10 years ago above the acceptable levels. Digital exam indicated no detectable masses. Two biopsies ensued in the next two years which found ZERO cancer. My urologist finally ordered an MRI guided biopsy based on suspect areas of the prostate. They finally found a small sample of Gleason 3+3 tissue, which I decided to “treat” with active surveillance.
My PSA continued to increase so we ultimately decided on radical prostatectomy. PSA has been undetectable since.
In my opinion, repeated biopsies can results in gland inflammation as well as risk bacterial infections, since they go through the rectal wall to get the tissue samples. These outcomes can aggravate PSA, resulting in a spiral into false readings.
“In my opinion, repeated biopsies can results in gland inflammation as well as risk bacterial infections”
I ended up in the emergency room after a prostrate biopsy a few years ago. I spent the entire day getting antibiotics through every orifice in my body. I will be going through another prostrate biopsy tomorrow at 8:30 based on the results of an MRI. Getting old sucks.