For me, for Rybelsus, on our medical plan, $7.50 per pill. Once per day. Strange directions. You take one pill with a couple sips of water only when you wake up and then NOTHING for half an hour to an hour after. THEN you can take your daily pills and food and liquid. One pill per day.
There are 3 stages for Rybelsus. You test your body with it at 3.5mg. For me, it took a couple weeks before any changes. Then, pretty suddenly, my appetite disappeared and I started losing weight continuously. Felt fine. No problems. Then felt better and better as I stayed on it. After a number of weeks, you plateau. Nothing else changes except you stop losing weight.
Then they move you to 7mg. Same identical thing happens. After a couple weeks you get your 2nd weight loss and eventual plateau.
Last stage is 14mg. Each time you’re checking for side effects. For me, never any. Same delayed weight loss and I haven’t reached the plateau yet.
I started Mounjaro a little over a year ago and am now at 10mg shots. Doc just upped me to 12.5mg which I will start when I am done with my 10mg pens. So, A1C was 9.3, now 5.8. Lost about 40 pounds. Have plateaued at 242-245 pounds and been that way about 6 months now. Hoping the 12.5mg will kickstart weight loss. No GI effects at all except some bloat if I eat too much. Some exhaustion on Day 3 - 4, but nothing bad. Diet has not changed much, except much more Thai food since my wife moved here in August (veggies and fruits, rice and noodles). My cholesterol has never been bad and never smoked and rarely drink alcohol. Just feel better all around. Oh, and I am 59.