I have read that cocaine and tobacco, known only in the Americas, was detected in the mummy of Ramses II aka Ramses the great.
This would imply that there was some sort of contact between Egypt and the Americas from around 2000 BC - at least.
People did get around by boat in extreme antiquity.
Apparently Thor Heyerdahl proved the ancient Egyptians could have gone across the Atlantic in a papyrus boat, if the boat were designed correctly and loaded properly.
https://www.britannica.com/topic/Ra
“I have read that cocaine and tobacco, known only in the Americas, was detected in the mummy of Ramses II aka Ramses the great.
This would imply that there was some sort of contact between Egypt and the Americas from around 2000 BC - at least.
People did get around by boat in extreme antiquity.”
I wish that was true for sure but there is question. While I absolutely believe they were seafaring way back then, the Cocaine Mummy has purportedly been debunked. They claim that there is a similar edible plant in the old world that also tests positive as Cocaine. Apparently it is supposed to be like the the Poppy seed muffin situation where simple Poppy seeds test positive as opiates.
That is the story anyway...
But then there is this... Cuneiform in ancient South America.
http://solomonsblondes.blogspot.com/2016/07/cuneiform-bowl-from-bolivia-crespi.html
Fanciful, but being coked up would explain how they built all those pyramids. ;-)