You don't start another therapy! Get it. Please explain how you stop the infusion that lasts for minutes and then start some other from of treatment. When the infusion is complete, it's over. Done. There is no possible way to “stop and immediately start a different strategy.” Your words — not mine.
Directly from the write up:
The paper found that patients who had an increase in absolute lymphocyte count (ALC) during the first 15 days after receiving a CAR-T infusion had a higher chance of a complete response and better progression-free survival than patients with a lower ALC at day 15. Knowing that the treatment may not work allows doctors to try other options more quickly.
“If doctors can identify patients who are more likely to have a poor response to BCMA CAR-T, other treatments can be explored or given earlier,” said Dr. Mejia Saldarriaga.
I never said the test was to determine that you should get CAR-T therapy. You seem to be getting that from somewhere else. I did say that a simple ALC test at 15 days determines if the CAR-T therapy you got from your doctor will work for you. Your doctor can help find other treatments. Your doctor will need to know that he can run an ALC test to determine that his CAR-T will work, or will be destined to fail, at just 15 days after the therapy. Until now, no one knew failure could be known at just 15 days. Get it?
What I am saying is straight from the write up.
It's not hard to understand, “icclearly.”
Oh, my. I can see you're really struggling to understand. Yep. Really struggling -- just like your naive notion about CAR-T.
CAR-T is not a pill you take. It is on the level of a major organ transplant. It is not something a local doc may even understand -- much less run a simple blood test at an "annual physical." Those are YOUR words -- not words from the report.
Your reply does not address my comments. I never said anything about the report from Weill Cornell. What I did reference is your flippant and misleading comments. It is quite clear you have no clue what you're talking about.
May I repeat your words.....
A very available, cheap blood test can tell you or your doctor that your multiple myeloma immunotherapy is working 15 days after starting it.....If it doesn’t look good at that point, immediately start a different therapy.
Where exactly can I get this cheap blood test? Is my family doctor at my annual visit going to run this test -- when he may not even know what CAR-T is (like you), much less the test?
You may already get this blood test as part of your annual physical. There’s no need to wait a lot of precious months now.
What? So I can get this at my annual physical by my local family doc? Really?
No need to wait precious months?? What wait? The infusion lasts minutes. The doctors who administer this treatment are the best of the best, and I know a few. None of these docs are going to wait months! There are many other tests that can be run in the period from 15 days to a month, and those docs may use the new test, but there are much more proven tests that will indicate the treatment worked or didn't work.
So, you see. It's not the words from the reports. It's your words and a total lack of understanding of what you are talking about. Any fool with a computer can find out about that test without being misled by your useless comments.
That's the deal. Get it?