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To: Red Badger

This article contains some misinformation. It refers to a “bone marrow transplant,” but this is not what is commonly done. A blood stem cell donor with matching HLA-type markers is stimulated to produce excess stem cells removed from the blood using a filter device (apheresis). The recipient is conditioned with chemotherapy to kill most of their stem cells before being infused with the donor stem cells. They can have a mix of both types (chimera) for a while until the donor cells dominate. Although the blood types can differ, the HLA matching is critical to avoid Graph vs. Host disease (GVHD).
What’s remarkable is that the donor and patient can be different genders. The patient’s blood DNA becomes the donor’s gender. Might make an interesting crime show twist.


16 posted on 07/07/2024 8:14:45 PM PDT by Dave Wright
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To: Dave Wright

Thank you. I noticed that too. I’m an allo SCT recipient. With a tad bit of gvhd. Been blessed as it can be a pretty serious ordeal. (You can see Post 11).
Just curious as to how you know this? It’s not typical info most know unless they have personal experience.


21 posted on 07/09/2024 7:15:43 AM PDT by HollyB
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