The article as posted didn’t mention whether it was RNA or DNA. I would imagine they would still use the lipid nanoparticle carrier for both since that was used to assist the RNA/DNA getting past the cell wall and into the ribosomes for RNA or into the nucleus if they used DNA.
Toxicological profile of lipid-based nanostructures: are they considered as completely safe nanocarriers?
” Due to unique physicochemical properties, they are able to cross many barriers, which is not possible for traditional drugs. Nevertheless, exposure to NPs and their following interactions with organelles and macromolecules can result in negative effects on cells, especially, they can induce cytotoxicity, epigenicity, genotoxicity, and cell death.”
https://pubmed.ncbi.nlm.nih.gov/32053030/
I actually looked it up as I have always been interested in all things genetic. They are using a viral vector as the cellular delivery system.
Basically infecting the entire body with a functional gene to counteract the failings of the incomplete damaged gene.
I don’t think the nanoparticles have the right vectoring characteristics for such a systemic whole body treatment.
Gene therapy is a completely different science than vax development.