[verum ago]

For anyone wondering, this is not an mRNA vaccine like the Covid ones. It's a recombinant protein vaccine that combines the target protein from the malaria parasite with one from Hepatitis B (simply to make it easier to purify). It contains and therefore conveys no genetic information.

It's not particularly effective, at only a 30% reduction of hospitalizations due to malaria. But this is still a huge improvement over our prior *nothing*- malaria kills over 600,000 people a year, and the vast majority of those are children. Put differently, out of ALL the deaths globally, malaria on its own accounts for over 1%. That's pretty damn significant for one communicable disease- most of the causes of death ahead of it are things like "heart disease" or "stroke" that have multiple causes. Attacking malaria is one of the most significant discrete (as opposed to the vague multi-origin causes of death mentioned above) global health improvements that can be made. It is probably the biggest single cause of childhood death- the only two causes of childhood mortality I can find listed ahead of it globally are "respiratory infections" and "diarrhea," both of which have a zillion actual causes.

[maddog55]

Bring back DDT and kill the source.

[mewzilla]

Being a recombinant protein vaxx, it likely uses and adjuvant and will probably require boosters.

If there’s an an adjuvant, wonder what it is?

And if boosters are required, that might make up for it being more expensive to produce than an mRNA vaxx.

Hope the pharmaceutical company isn’t screwing the public.

[mewzilla]

More details here, from 2019, including on boosters and adjuvants...

RTS,S/AS01 vaccine (Mosquirix™): an overview