Destroying the cartels with extreme prejudice would be a critical part of securing our borders from invasion. At 12:00:01 EST on Inauguration Day, all 5 branches of the US Military could/would/should launch a coordinated attack on every single cartel known to the US, wiping them off the face of the earth.
It would also send a message to our enemies elsewhere that there is a seismic shift in US policy to include robust protection of our national sovereignty and defense.
Perhaps.
But we should concentrate on destroying them out of the US first.