ITP is caused by antibodies that the patient produces against platelets. The article states that their treatment “ reducing the necessity for platelet transfusions.” Transfusing platelets to these patients is not only ineffective but counterproductive because it stimulates the production of additional antibodies that destroy platelets. The combination therapy sounds good but how long does it last? Most patients with relapsing ITP end up with a splenectomy which will alleviate the platelet shortage in the body.
I had ITP 10 years ago. Steroids and IVg didn’t work. Put me on Promacta, which worked, then weaned off it.