“It would be interesting to know what part of the world these HLA folks’ predecessors came from...Northern European? Mediterranean? Where?”
A great question. The women I noted in my response #8 below, not getting Covid in spite of living with those who did, were/are descendants of the upper UK and Western Europe.
They are fair skinned, blonde or ginger hair and basically very healthy women. None are overweight.
https://freerepublic.com/focus/chat/4169320/posts?page=8#8
If I understand how the HLA works on the antigen layer, the more “thoroughbred” you are, the simpler your antigen layer is in your cells. Therefore, it’s easier to detect anomalies and reject those cells (as viruses). But if you’ve got a lot of flavor in your ancestry, your antigen layer can be a bit noisy and it’s hard to recognize a virus anomaly from regular variations.
Thank you. Perhaps it was the genes from my mother’s Swedish/German/Viking forebears that saved me from covid.
A great question. The women I noted in my response #8 below, not getting Covid in spite of living with those who did, were/are descendants of the upper UK and Western Europe.
They are fair skinned, blonde or ginger hair and basically very healthy women. None are overweight.”
Fair skinned blonde or ginger-haired people are also more likely to carry some Neanderthal genes.I am a blonde and never got Covid although my family and everyone I know got it.
Maybe those genes have had longer exposure to all kinds of disease than the later groups of people.
Same here. That's where about 50 percent of my DNA comes from. Tested positive for Covid twice with no symptoms.