I am having trouble understanding your question. Do you mean the SARS1 experimental vaccines that bombed out in the animal testing? How do know the genome was “never isolated in a lab setting”? Can you post a link or something?
Look it up. Covid 19 has never been conclusively ever isolated in Lab setting.
And you are right in that there is no Coronavirus Vaccine that can ever be made due to the fact it Mutates constantly and there was failure at ever attempt at the Animal testing stage, all the lab animals died.