Hoe lee sheet!
Published online 2020 Nov 3.
“Here, we purified anti-spike-S1 IgYs from hens that were immunized with the S1 domain of the SARS-CoV-2 spike protein and interrogated their ability to neutralize SARS-CoV-2 pseudovirus using Hela cells with overexpressed human ACE2. “
Note the hens were immunized.
https://www.sciencedirect.com/science/article/pii/S1567576920336390?via%3Dihub