I have a Dell Latitude 3300 and in that slot you would have to use a smaller M.2 a 2 inch or less one and I have one from an upgrade maybe I should try it out ,LOL
How old is that 3300?
Yes, the “2242” describes the dimension (22 mm x 42 mm) of the M.2 drive needed to fit.
If you do try that out, the results would be interesting (but may vary with the bios and motherboard). If that SATA M.2 is 500GB (or maybe even 256 GB) do you want to sell it?