If I had to take one of these, I would personally prefer Adalimumab, as tumor necrosis factor (TNF) alpha influences all sorts of other often oit-of-control inflammatory processes. Interestingly, many antioxidants reduce TNF to achieve their benefit. Diet and exercise can help with this, too.
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I second your assessment. TNF alpha is at the headwaters of cytokines. Look at the cytokine response lists of so many inflammatory diseases and you find TNF alpha most of the time.
I wonder if controlling tnf would be a way to defeat covid for those most at risk? Crohns and related diseases are where the body turns on itself and attacks it, destroying systems like digestive system, and covid I think is where the body turns on itself too? (Causing cytokin storms)?