[LilFarmer]

I am leery of any drug ending in “mab” as many of them were developed using humanized mice (including this drug). List is here: https://en.wikipedia.org/wiki/List_of_therapeutic_monoclonal_antibodies

Some of these mice are humanized with fetal tissue/fetal stem cells and it is not always easy to find out which ones. Here are some:

https://www.fetalindustry.com/post/aborted-baby-organs-used-to-humanize-mice-for-covid-19-vaccine-and-therapeutic-testing

[LilFarmer]

Under “Ethical Statement”
Humanized NOG-EXL mice (highly immunodeficient NOG mice) expressing human GM-CSF and human IL-3, engrafted with CD34 human stem cells

http://www.anaptysbio.com/wp-content/uploads/Preclinical-characterization-of-dostarlimab.pdf