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To: hinckley buzzard

It’s a start, but too small to be conclusive. There needs to be a larger trial.


22 posted on 06/07/2022 1:30:48 PM PDT by philippa
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To: philippa

By definition, a phase II trial is a small number of people.

Pre-clinical is animal studies/lab studies. Phase I is determining how large a dose is SAFE in humans (not effective, just SAFE). Phase II is determining if it is EFFECTIVE at levels below the phase 1 safety margins.

There doesn’t need to be “another trial.” This (or any other dug with similar profiles) just continues on through the next phase of testing. If it is shown to be effective in Phase II trials, it moves to Phase III. Phase III is expanding to a much larger group. They don’t just look at a few monkeys or petri dishes and then release this or any other drug on a huge number of people.

There is value and relevance in results of EVERY phase of testing, including failure levels. This drug shows a lot of promise on a small, well-controlled group of people.


25 posted on 06/12/2022 7:59:26 PM PDT by JustOneStarfish ("The best way to predict the future is to create it." ~~~Peter Drucker)
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