[gleeaikin]

When I have some time I will try to find my creatinine levels (I hate trying to find my lab results on line), and prepare a list of my supplements and amounts. I have been taking 400IU of Vitamin E, usually mixed tocopherols or d-alpha form for 50 years. My varicose veins are happy and mostly invisible. I have never used tocotrienols or the other item you suggested and will have to check them out on line to decide if I should try them and can afford them. What is the eGFR as opposed to the GFR?

Fifty-five years ago I had hyperglycemia and would have to eat every 2 hours. I had hunger panic attacks. Now I can go for a number of hours without a meal with no difficulty. I do look at my blood sugar levels when I get my lab results and have done a glucose tolerance test in the past. Doctor has not suggested it in the past few years. A maternal aunt was diabetic on insulin. Thank you for the suggestions.

[ConservativeMind]

I looked further into the study, from PubMed, instead.

https://pubmed.ncbi.nlm.nih.gov/31903178/

The specific form used had much higher tocotrienols than the standard form of the EVNol formula.

This is the form:

TOCOVID
https://smile.amazon.com/Tocovid-Suprabio-MG-Palm-Tocotrienols-softgels/dp/B01DU8P3CI

That concentration is nearly 200 mg of tocotrienols a pill.

I’d suggest getting the Swanson Double Strength Tocotrienols instead, on one of their many sales at the Swanson website.

It’s possible to get a bottle of 60 capsules of 100mg pure tocotrienols for under $16, making the two 200 mg doses a day cost about $1/day.

Don’t take extra Vitamin E at the time, as it interferes with absorbtion and activity of the tocotrienol form. I can dig up the information on this, if needed.

[ConservativeMind]

From the full text study, it appears there was a 13% difference in eGFRs of the supplemented group versus the control group.

https://journals.sagepub.com/doi/10.1177/2042018819895462?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

The two groups had Type 2 diabetes, and, sadly, the unchecked creatinine increase in the control group was bad, while there was some actual improvement in the supplemented group, more than countering the apparent expected creatinine increase they would have had.

[ConservativeMind]

This is interesting. The 13% difference developed many months after the initial 12-week tocotrienols were administered. It was less than half that difference at the 12-week completion.

Somehow the tocotrienols effected a permanent change for the better, at least for 9 months (the last blood tests collected from all).

[ConservativeMind]

I came across this site which describes multiple approaches to reduce creatinine:

https://bloodtestsresults.com/creatinine-blood-test-normal-creatinine-levels-age/

It appears a common supplement, Alpha-Liopic-Acid, can help.

We take either the Jarrow Formulas time-release form or the Doctor's Best R-Lipoic-Acid form, but the least expensive to trial would be a standard Alpha-Lipoic-Acid form.

[ConservativeMind]

Here’s another reference to generally help.

It, too, describes Alpha Lipoic Acid as a possibility:

https://www.kidneycoach.com/kidney-symptoms/creatinine-levels/